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Chagas disease is named after the Brazilian physician Carlos Chagas, who discovered the disease in 1909. It is caused by the parasite Trypanosoma cruzi, which is transmitted to animals and people by insect vectors and is found only in the Americas (mainly, in rural areas of Latin America where poverty is widespread).

Chagas disease (T. cruzi infection) is also referred to as American trypanosomiasis. In the United States, Chagas disease is considered one of the Neglected Parasitic Infections, a group of five parasitic diseases that have been targeted by Centers for Disease Control (CDC) for public health action.

Symptoms of Chagas disease include fever, fatigue, body aches, headache, a rash where the parasite entered the body and swelling around the eyelids. With treatment by a medical professional these symptoms usually fade, but cardiac issues, intestinal problems, and other more serious complications can sometimes develop.